TAG:
mass spectrometry
All-Star Vitamin D Panel Looks at Lab Challenges
CEO SUMMARY: Need proof that the issues surrounding today’s Vitamin 25(OH) D are of keen interest to laboratory professionals? Not only did the EXECUTIVE WAR COLLEGE’S in depth sessions on Vitamin D draw a large audience and enthusiastic participation by attendees, but within…
UMass Lab’s Experience With Vitamin D Methods
CEO SUMMARY: As it developed a home brew mass spec assay for Vitamin 25(OH) D to meet the request of some client physicians, the laboratory at the University of Massachusetts Medical Center quickly recognized several challenges. First, there were fundamental differences in the nu…
DARK REPORT and Editor Michel Earn National Reporting Award
FOR THE SECOND TIME in recent years, Editor Robert L. Michel and THE DARK REPORT have won a national award for “Best Investigative Reporting.” In Washington, DC, last month, at the Specialized Information Publishers Association (SIPA) annual conference, Editor Michel learned tha…
Need Rigorous Validation For Home Brew Assays
CEO SUMMARY: National headlines about erroneous Vitamin D results are a reminder to the lab industry of the imprecision and risks associated with home brew testing. According to one laboratory expert, every laboratory-developed test (LDT) must meet two high standards. On…
Molecular Advances Soon To Reshape Anatomic Path
CEO SUMMARY: Early this month, the second annual Molecular Summit assembled molecular first movers and early adopters to discuss their efforts to integrate molecular imaging and molecular diagnostics in patient care. One clear message emerged from two days of presentations and di…
When Does Cost Cutting Affect a Lab’s Quality?
CEO SUMMARY: Many lab professionals note the irony that a laboratory so publicly committed to Six Sigma quality management methods is now identified with the single largest episode of systemic failure in lab test accuracy. Looking in from the outside, some pathologists suggest th…
Inaccurate Results + Quest Dominates News Cycle
CEO SUMMARY: Most laboratory professionals don’t know it yet, but significant changes occurred to the entire lab industry last week. After Quest Diagnostics Incorporated acknowledged that it was retesting tens of thousands of patients because 7% of the Vitamin D results it repo…
Quest Discusses Use of Mass Spec Methodology
CEO SUMMARY: Having made the decision to perform nearly all Vitamin 25(OH) D testing by liquid chromatography–tandem mass spectrometry (LC–MS/MS), Quest Diagnostics Incorporated found the transition to be challenging. That was particularly true as the volume of Vitamin D specimens tri…
Quest Diagnostics Explains Confidence in LC-MS/MS Method
ONE ASPECT IN THE DEBATE about the integrity of Vitamin D tests produced by liquid chromatography–tandem mass spectrometry (LC 0150MS/MS) is the discussion about how this method can produce results that are significantly higher than those produced by immunoassay-based methods. Quest Diagnostics add…
Vitamin D Test Expert Discusses Mass Spec
CEO SUMMARY: Those labs performing Vitamin 25(OH) D testing by mass spectrometry face an interesting challenge. For more than two decades, physicians, patients, and a majority of credible clinical studies have accepted RIA and IA Vitamin 25(OH) D results as a familiar standard. That is wh…
CURRENT ISSUE
Volume XXXII, No. 6 – April 21, 2025
Now that a federal judge has vacated the FDA’s LDT rule, The Dark Report analyzes the judgement and notes the various steps the FDA could take in response. Also, lab testing at pharmacies is proving to be less successful than was once anticipated.
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