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Histology

Histology is a branch of anatomy that deals with the study structure of animal and plant tissues that is only discernible with a microscope. It is also called microscopic anatomy, as opposed to gross anatomy, which involves structures that can be observed with the naked eye. The word “histology” is derived from two Greek words: histo, which means “tissue,” and logos, which means “study.”

Histopathology, the microscopic study of diseased tissue, is an important tool used in anatomical pathology, as accurate diagnosis of cancer and other diseases usually requires histopathological examination of samples.

Histological studies are often carried out by examining a thin slice (called a “section”) of tissue under a light microscope or an electron microscope on a prepared slide.

In order to distinguish different biological structures more easily and accurately, histological stains are often used to add colors to, or enhance the colors of, certain types of biological structures to allow them to be more easily differentiated from other types of structures. Staining is employed because biological tissue has little inherent contrast when observed using either light or electron microscopes.

Trained physicians, frequently licensed clinical pathologists, are the personnel who actually perform histopathological examinations and provide diagnostic information based on their observations of the tissues being tested.

The trained personnel who prepare histological specimens for examination may go by a number of titles, including:

Their field of study is called histotechnology.

Histology has seen recent changes as technological advances in automation have influenced the field. Automation allows for the reduction of the workload of manual task needed to prepare and track histology specimens. Artificial intelligence also is playing a growing role in supporting the analysis of sections, supporting anatomic pathologists during their examinations of samples.

Acute Histotech Shortage Grows Across the USA

CEO SUMMARY: Pathology laboratories are enjoying steady increases in specimen volume and revenue as new molecular assays gain acceptance by clinicians. However, the supply of histotechnologists is failing to keep pace with growth in the volume of tissue-based testing. One executive who pl…

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Pathology Lets the Oncology Cat Out of the Bag

BECAUSE OF GENETIC TECHNOLOGY, the profession of anatomic pathology may be poised for a golden age. The range of new technologies and diagnostic assays heading for clinical use have the potential to give pathologists the ability to detect disease with greater precision. They will also allow pathologi…

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Ventana & Cytyc Fall Short, Danaher Wins the Prize

WHEN Danaher Corporation’s high bid for Vision Systems Limited of Melbourne, Australia, was accepted last month, it appeared to be simply another acquisition by a large U.S. manufacturer. But, in fact, there are four reasons this transaction is significant to patho…

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Some Random Insights About LabCorp’s Thinking

CEO SUMMARY: Having scooped up a number of mid-sized laboratory companies in recent years, Laboratory Corporation of America is working to integrate these operations and continue to expand its market share. In a recent conversation with financial analyst Bill Bonnello of Wachovia Securiti…

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Office-Based Docs Want Anatomic Path Revenues

CEO SUMMARY: Specialist physicians think they’ve found gold in anatomic pathology services. Indifferent regions of the United States, urologists and gastroenterologists are taking active steps to cut themselves a piece from the anatomic pathology revenue pie. Some physician groups are b…

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Labs Taught Physicians How to Do TC/PC Deals

CEO SUMMARY: As many pathology groups discover that their best urology and gastroenterology clients are taking serious steps to do their own anatomic pathology, they ask a basic question: How did their best-referring…

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Technical/Professional Billing Triggers Strong Opinions

IT’S A TREND WHICH IS GAINING THE NOTICE of growing numbers of pathologists. Physician groups are taking steps to directly engage pathologists to diagnose cases. The term “TC/PC” is often used to describe situations where two different providers provide the technical component…

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Many Trends in AP Spell Lots of Change Ahead

CEO SUMMARY: Every second year, THE DARK REPORT releases its list of key trends in anatomic pathology. These trends help shape an understanding about the state of the pathology profession. Our current list includes 11 identifiable trends. This is not an auspicious sign for pathologists wh…

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Failure of AD Pathlabs: Structural Weakness?

CEO SUMMARY: AD PathLabs is the latest in a string of business disappointments. Over the past decade, a number of anatomic pathology companies have proven that they can grow rapidly—attracting substantial volumes of specimens. But these companies seem to hit a financial wall that leads …

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Bio-Reference Labs Develops Regional & Niche Strategies

CEO SUMMARY: Bio-Reference Laboratories, Inc. (BRLI) of Elmwood Park, New Jersey is a lab company on a roll. In just five years, it has grown from $66 million to more than $160 million in annual revenues. For regional laboratories across the country, BRLI’s business strategies demon…

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