Tag: tandem mass spectrometry

Mass Spec Tests Struggle To Gain Insurers’ Attention

CEO SUMMARY: Since 2014, a toxicology lab at the University of Colorado has used mass spectrometry to offer low-cost, accurate multi-analyte test panels that can detect hundreds of therapeutic drugs and drugs of abuse. However, CU Toxicology’s chief medical officer says health insurers are slow to accept this diagnostic technology, despite its demonstrated clinical benefit

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Our Editor Gets His Vitamin D Test Results From 9 Different Labs

CEO Summary: Editor-In-Chief Robert L. Michel gave blood for the cause and it’s another laboratory industry first! To understand what doctors and patients see as national labs use different methodologies and reference ranges to report Vitamin 25(OH) D results, his blood was tested 24 times by nine laboratories. The results were unveiled at the Executive

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All-Star Vitamin D Panel Looks at Lab Challenges

CEO SUMMARY: Need proof that the issues surrounding today’s Vitamin 25(OH) D are of keen interest to laboratory professionals? Not only did the EXECUTIVE WAR COLLEGE’S in depth sessions on Vitamin D draw a large audience and enthusiastic participation by attendees, but within weeks, two of the lab industry’s most-watched magazines published headline stories about

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DARK REPORT and Editor Michel Earn National Reporting Award

FOR THE SECOND TIME in recent years, Editor Robert L. Michel and THE DARK REPORT have won a national award for “Best Investigative Reporting.”

In Washington, DC, last month, at the Specialized Information Publishers Association (SIPA) annual conference, Editor Michel learned that judges had bestowed the First Place award for “Best Investigative Reporting” to THE DARK

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Need Rigorous Validation For Home Brew Assays

CEO SUMMARY: National headlines about erroneous Vitamin D results are a reminder to the lab industry of the imprecision and risks associated with home brew testing. According to one laboratory expert, every laboratory-developed test (LDT) must meet two high standards. One, accuracy, reproducibility, and transferability of the test result number. Two, a reference range that

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Quest Discusses Use of Mass Spec Methodology

CEO SUMMARY: Having made the decision to perform nearly all Vitamin 25(OH) D testing by liquid chromatography–tandem mass spectrometry (LC–MS/MS), Quest Diagnostics Incorporated found the transition to be challenging. That was particularly true as the volume of Vitamin D specimens tripled at the nation’s largest lab company during the period May 2006 to May 2008.

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Quest Diagnostics Explains Confidence in LC-MS/MS Method

ONE ASPECT IN THE DEBATE about the integrity of Vitamin D tests produced by liquid chromatography–tandem mass spectrometry (LC 0150MS/MS) is the discussion about how this method can produce results that are significantly higher than those produced by immunoassay-based methods. Quest Diagnostics addressed this point directly.

In response to questions from THE DARK REPORT, Wael Antoine

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