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Histology

Histology is a branch of anatomy that deals with the study structure of animal and plant tissues that is only discernible with a microscope. It is also called microscopic anatomy, as opposed to gross anatomy, which involves structures that can be observed with the naked eye. The word “histology” is derived from two Greek words: histo, which means “tissue,” and logos, which means “study.”

Histopathology, the microscopic study of diseased tissue, is an important tool used in anatomical pathology, as accurate diagnosis of cancer and other diseases usually requires histopathological examination of samples.

Histological studies are often carried out by examining a thin slice (called a “section”) of tissue under a light microscope or an electron microscope on a prepared slide.

In order to distinguish different biological structures more easily and accurately, histological stains are often used to add colors to, or enhance the colors of, certain types of biological structures to allow them to be more easily differentiated from other types of structures. Staining is employed because biological tissue has little inherent contrast when observed using either light or electron microscopes.

Trained physicians, frequently licensed clinical pathologists, are the personnel who actually perform histopathological examinations and provide diagnostic information based on their observations of the tissues being tested.

The trained personnel who prepare histological specimens for examination may go by a number of titles, including:

Their field of study is called histotechnology.

Histology has seen recent changes as technological advances in automation have influenced the field. Automation allows for the reduction of the workload of manual task needed to prepare and track histology specimens. Artificial intelligence also is playing a growing role in supporting the analysis of sections, supporting anatomic pathologists during their examinations of samples.

Process Improvement Coming to Healthcare

CEO SUMMARY: One new byword coming to healthcare in the United States is the “continuously-learning healthcare system.” At the upcoming Lab Quality Confab in San Antonio next month, lab managers and pathologists can learn more about how to achieve and sustain continuous improvement in…

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Leica, Aperio, Myriad, AMP, Hologic, Gen-Probe

LEICA BIOSYSTEMS TO ACQUIRE APERIO FOR THE SECOND TIME IN AS MANY YEARS, a global leader in histology systems and products has announced that it will acquire one of the leading digital pathology companies. This time it is Leica Biosystems of Nussloch, German…

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MD Self-Referral Issues Target of Utilization Study

CEO SUMMARY: When it comes to the in-office ancillary service (IOAS) exception to physician self-referral, the issue of in-clinic pathology services has become a hot potato. Publication in Health Affairs of a study of urologists’ self-referral of their patients for anatomic pathology se…

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QMS Helps Ontario Labs Cut Errors, Improve TAT

CEO SUMMARY: In Brampton and Etobicoke, Ontario, the hospital laboratories of William Osler Health System are using the quality management system of ISO 15189 to stay ahead of two powerful trends. Combining the QMS with Lean methods allows the labs’ management and staff to continuously …

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Quest Diagnostics and LabCorp Report Q-4, Full Year Earnings

IN RECENT WEEKS, each of the nation’s two largest public laboratory companies reported earnings for fourth quarter 2011 and full year 2011. Organic growth at both lab companies continues at low single-digit rates. This continues the pattern of relatively modest growth that has been posted by each …

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Shaw & Adelman Successful Support of Lab Networks Need Hospital Leadership

CEO Summary: In the second installment of our exclusive two- part interview, the executive directors of two regional laboratory networks formed in the 1990s (one in Michigan and one in Washington State) share their assessment of why their respective lab networks have performed strongly ov…

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Allina Opens State-of-the-Art Central Laboratory Facility

THIS MONTH, THE NATION’S NEWEST “designed from scratch” clinical laboratory facility began operating in Minneapolis, Minnesota. It is the central laboratory of Allina Hospitals & Clinics and its design is rooted in Lean and similar process improvement and workflow principle…

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Anatomic Path Insourcing Expected to Be Ongoing

CEO SUMMARY: Insourcing of anatomic pathology services by office-based physicians has been especially prevalent and is increasing among three specialties (gastroenterology, urology, and dermatology), according to a survey conducted last month. Survey respondents also indicated that the tr…

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In-Practice Histology Lab Splits Biopsies; ID’s Patient with DNA

In response to continuing requests by clients and readers of THE DARK REPORT, this issue institutes a new feature titled “Lab Fraud Watch.” It will provide information about activities in the medical laboratory testing marketplace which could be interpreted as violatin…

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August 15, 2011 “Intelligence: Late Breaking Lab News”

Last Friday, the acquisition of Southern Diagnostic Laboratories, Inc., of Birmingham, Alabama, was announced by Solstas Lab Partners of Greensboro, North Carolina. Steve Boyd, who is the Founder and CEO of Southern Diagnostics, will become a Senior Vice President at…

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