March 26, 2018 Intelligence: Late Breaking Lab News

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On March 6, one of the lab industry’s long-serving executives and consultants, Jack Mattice, PhD, of Vancouver, Wash., died from flu complications. He was 77 years old. Mattice earned a PhD in medical microbiology from University of Oregon. Within a few years, he was handling market development for United Medical Laboratories (UML), of Portland, Ore. UML reached a then-record volume of 25,000 specimens per day and was acquired before 1980. Mattice, Charlie Dexter, and James Root, MBA, founded Lancet Labs in Portland during the 1970s.

MORE ON: Mattice

Lancet Labs was itself acquired just a few years later by MetPath, Inc. Following that sale, Jack Mattice, along with partner Charles Dexter, purchased an ownership interest in Physicians Medical Laboratories (PML) in Portland, Ore. When PML was sold to Nichols Institute in 1989, Mattice left to concentrate on growing his lab and medical consulting business, J.A. Mattice & Associates. The website states his consulting company had more than 200 hospitals as clients.

40% ERROR RATE IN GENE TESTING?

This month, Genetics in Medicine, a Nature journal, reported “that researchers at a clinical laboratory re-tested 49 patients’ samples and compared them to raw data from their direct-to-customer (DTC) tests. Two in five variants in the DTC information were incorrectly reported.” The study shows the complexity associated with genetic testing, given the current state of sequencing technology. The lead researcher, genetics counselor Stephany Leigh Tandy-Connor from Ambry Genetics, stated, “Such a high rate of a false positives in this particular study was unexpected. Of all the BRCA1 and 2 variants in the study, for example, 17 were correctly identified, while eight were false positives. Across the study, 94% of the false-positive calls were for cancer-related genes.”

TRANSITIONS

  • TriCore Reference Laboratories of Albuquerque, N.M., appointed pathologist Michael Crossey, MD, PhD, as its President and CEO. Crossey has been affiliated with TriCore since 1997.

That’s all the insider intelligence for this report.
Look for the next briefing on Monday, April 16, 2018.

dark_daily_logoHave you caught the latest e-briefings from DARK Daily? If so, then you’d know about …

…a change in lab accreditation requirements at The Joint Commission that now allows pathologists who work in independent reference laboratories to provide diagnostic services for CLIA-Approved hospital labs without the need for additional credentialing and privileging.

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